An efficient asymmetric synthesis of (?)-lupinine??
Chemical Communications Pub Date: 2014-06-09 DOI: 10.1039/C4CC02135E
Abstract
The asymmetric synthesis of (?)-lupinine was achieved in 8 steps, 15% overall yield and >99?:?1 dr from commercially available starting materials. The strategy used for the construction of the quinolizidine scaffold involved reaction of an enantiopure tertiary dibenzylamine via two sequential ring-closures which both occurred with concomitant N-debenzylation.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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