An artificial receptor synthesized by surface-confined imprinting for the recognition of acetylation on histone H4 K16?

Chemical Communications Pub Date: 2015-03-24 DOI: 10.1039/C4CC09787D

Abstract

A novel artificial receptor has been synthesized using surface-confined imprinting for the recognition of lysine acetylation in histone H4. The material has high recognition fidelity and epitope affinity. It was demonstrated that acetylated Lys plays a role in binding site creation and peptide imprinting can be performed in phosphate buffer.

Graphical abstract: An artificial receptor synthesized by surface-confined imprinting for the recognition of acetylation on histone H4 K16
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