Towards the improvement of the synthesis of novel 4(5)-aryl-5(4)-heteroaryl-2-thio-substituted imidazoles and their p38 MAP kinase inhibitory activity?
Organic & Biomolecular Chemistry Pub Date: 2007-12-21 DOI: 10.1039/B717605H
Abstract
A series of 2-alkylsulfanyl-4-(4-fluorophenyl)-5-(2-aminopyridin-4-yl)-substituted imidazoles was prepared and interaction possibilities of the 2-thioether moiety with phosphate/ribose binding pockets of p38
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4