Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase?

Organic & Biomolecular Chemistry Pub Date: 2017-09-14 DOI: 10.1039/C7OB02171B

Abstract

Monodisperse thermoresponsive cyclodextrins appended with benzenesulfonamides were demonstrated to reversibly regulate the enzymatic activity of carbonic anhydrase, which was found to be dependent on both scaffold effect and thermoresponsiveness.

Graphical abstract: Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase
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