Synthesis of novel pyrazolylbiscoumarin derivatives using FeTUD-1 as a mesoporous solid acid catalyst?

RSC Advances Pub Date: 2013-10-02 DOI: 10.1039/C3RA43913E

Abstract

A series of novel pyrazolyl biscoumarins was synthesized at 80 °C in a one pot procedure using an Fe3+ incorporated mesoporous silicate catalyst (FeTUD-1). The wormhole structured FeTUD-1 catalyzed the condensation of pyrazole aldehyde (1,3-diphenyl-1H-pyrazole-4-carbaldehyde) and 4-hydroxy coumarin to give the product in ～85% yield. XRD and N2 sorption studies of FeTUD-1 confirmed its amorphous, mesoporous nature, which possessed a large surface area of 638 m2 g?1 and a pore diameter of 9.4 nm. The nature of Fe3+ ion co-ordination within the silica matrix was evaluated by different techniques including diffuse reflectance UV-Vis, FTIR, and EPR. FeTUD-1 possessed both Br?nsted and Lewis acidity, as measured by FTIR of pyridine adsorption, that are responsible for the observed activities.

Graphical abstract: Synthesis of novel pyrazolylbiscoumarin derivatives using FeTUD-1 as a mesoporous solid acid catalyst
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