Synthesis of indazoles from 2-formylphenylboronic acids?
RSC Advances Pub Date: 2021-06-28 DOI: 10.1039/D1RA04056A
Abstract
A method for the synthesis of indazoles was developed which involves a copper(II) acetate catalysed reaction of 2-formylboronic acids with diazadicaboxylates followed by acid or base induced ring closure. Hydrazine dicarboxylates were also shown as competent reaction partners for the synthesis of indazoles, however, they required a stoichiometric amount of copper(II) acetate for the C–N bond formation step. The transformation can be efficiently performed as a two step-one pot procedure to give a range of 1N-alkoxycarbonyl indazoles.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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