Silver(i)-catalyzed addition of pyridine-N-oxides to alkynes: a practical approach for N-alkenoxypyridinium salts?
Organic & Biomolecular Chemistry Pub Date: 2018-12-26 DOI: 10.1039/C8OB02907E
Abstract
A smooth catalytic approach to N-alkenoxypyridinium salts by using pyridine-N-oxides as the nucleophilic partner with alkynes under acidic conditions has been developed. This method uses different Ag(I) salts, with 5% AgOAc being the most efficient, to provide an efficient, practical and alternative way to obtain valuable N-alkenoxypyridinium salts with good to excellent yields (up to 93%).
Recommended Literature
- [1] An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon? Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu MaRSC Adv., 2021,11, 37631-37642 10.1039/D1RA04788D
- [2] An antioxidant self-healing hydrogel for 3D cell cultures? Lei Yang,Yuan Zeng,Haibo Wu,Chunwu Zhou,Lei TaoJ. Mater. Chem. B, 2020,8, 1383-1388 10.1039/C9TB02792K
- [3] Alternative synthesis of the anti-baldness compound RU58841? RSC Adv., 2014,4, 14143-14148 10.1039/C4RA00332B
- [4] An astrophysically-relevant mechanism for amino acid enantiomer enrichment Stephen P. Fletcher,Richard B. C. Jagt,Ben L. FeringaChem. Commun., 2007, 2578-2580 10.1039/B702882B
- [5] An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands? Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier FelpinReact. Chem. Eng., 2019,4, 1608-1615 10.1039/C9RE00096H
- [6] An investigation of new infrared nonlinear optical material: BaCdSnSe4, and three new related centrosymmetric compounds: Ba2SnSe4, Mg2GeSe4, and Ba2Ge2S6? Kui Wu,Zhihua Yang,Shilie PanDalton Trans., 2015,44, 19856-19864 10.1039/C5DT03215F
- [7] Acetyl protected thiol methacrylic polymers as effective ligands to keep quantum dots in luminescent standby mode? Marta Liras,Isabel Quijada-Garrido,Marta Palacios-Cuesta,Sonia Mu?oz-Durieux,Olga GarcíaPolym. Chem., 2014,5, 433-442 10.1039/C3PY00987D
- [8] An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement? Piotr Szcze?niak,Sebastian SteckoRSC Adv., 2015,5, 30882-30888 10.1039/C5RA02818C
- [9] An atom-economical protocol for direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes in water? Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha RaoGreen Chem., 2017,19, 4446-4450 10.1039/C7GC01483J
- [10] An ion-exchange method for determining paraquat residues in food crops Analyst, 1965,90, 99-106 10.1039/AN9659000099
Journal Name：Organic & Biomolecular Chemistry
research_products
-
CAS no.: 89640-58-4
![1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol](https://ossimg.kuujia.com/scimg/1271000/1270529-38-8x500.png)
![N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide](https://ossimg.kuujia.com/scimg/1444500/1444113-98-7x500.png)
![2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid](https://ossimg.kuujia.com/scimg/2138500/2138166-62-6x500.png)
![2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide](https://ossimg.kuujia.com/scimg/2034500/2034271-14-0x500.png)