Regio- and stereoselective intermolecular carbolithiation reactions
RSC Advances Pub Date: 2020-09-02 DOI: 10.1039/D0RA06101H
Abstract
The inter-molecular carbolithiation of unfunctionalized and functionalized alkenes, followed by electrophile trapping, provides a versatile and useful tool for the construction of complex molecular systems, allowing the simultaneous creation of up to two novel carbon–carbon or carbon–heteroatom bonds. In this review a full overview on inter-molecular carbolithiation processes is reported, with a main focus on the chemo-, regio- and stereo-control of the reaction and on the strategies for asymmetric processes.
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Journal Name:RSC Advances
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CAS no.: 89640-58-4