New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity?

Organic & Biomolecular Chemistry Pub Date: 2010-06-01 DOI: 10.1039/C003964K

Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

Graphical abstract: New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity
Recommended Literature