Nanoparticle modified QCM-based sensor for lipase activity determination

Analytical Methods Pub Date: 2013-06-27 DOI: 10.1039/C3AY41047A

Abstract

A highly sensitive lipase activity sensor was developed and tested. It is based on the application of SiO2 nanoparticle loaded olive oil as a lipase substrate, deposited on a QCM crystal. The heavier nanoparticles’ release during the substrate enzymatic degradation causes a QCM frequency response enhancement proportional to the nanoparticle/substrate mass ratio.

Graphical abstract: Nanoparticle modified QCM-based sensor for lipase activity determination
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