Mn(iii)-mediated reactions of 2-isocyanobiaryl with 1,3-dicarbonyl compounds: efficient synthesis of 6-alkylated and 6-monofluoro-alkylated phenanthridines?
Chemical Communications Pub Date: 2014-09-01 DOI: 10.1039/C4CC05324A
Abstract
Mn(III)-mediated reactions of 2-isocyanobiaryls with 1,3-dicarbonyl compounds were described for the construction of 6-alkylated and 6-monofluoro-alkylated phenanthridines in moderate to good yields. The reaction involves formation of two new C–C bonds and one C–C bond cleavage.
Recommended Literature
- [1] An alkynylboronatecycloaddition strategy to functionalised benzyne derivatives? James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. HarrityChem. Commun., 2010,46, 5154-5156 10.1039/C0CC01345E
- [2] An antioxidative galactomannan extracted from Chinese Sesbania cannabina enhances immune activation of macrophage cells? Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang ChengFood Funct., 2020,11, 10635-10644 10.1039/D0FO02131H
- [3] An analyte-triggered artificial peroxidase system based on dimanganese complex for a versatile enzyme assay? Suji Lee,Min Su HanChem. Commun., 2021,57, 9450-9453 10.1039/D1CC03638F
- [4] Acetyl group orientation modulates the electronic ground-state asymmetry of the special pair in purple bacterial reaction centers P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. BudaPhys. Chem. Chem. Phys., 2011,13, 10270-10279 10.1039/C1CP20213H
- [5] Aggregation-induced chiral symmetry breaking of a naphthalimide–cyanostilbene dyad? Xin Li,Liangliang Zhu,Sai Duan,Yanli Zhao,Hans ?grenPhys. Chem. Chem. Phys., 2014,16, 23854-23860 10.1039/C4CP04070H
- [6] An aqueous ammonia sensor based on an inkjet-printed polyaniline nanoparticle-modified electrode Karl Crowley,Eimer O'Malley,Aoife Morrin,Malcolm R. Smyth,Anthony J. KillardAnalyst, 2008,133, 391-399 10.1039/B716154A
- [7] Aggregation-induced emission enhancement in halochalcones? Patricia A. A. M. Vaz,Jo?o Rocha,Artur M. S. SilvaNew J. Chem., 2016,40, 8198-8201 10.1039/C6NJ01387B
- [8] Aggregation-induced emission leading to two distinct emissive species in the solid-state structure of high-dipole organic chromophores? Felix Witte,Philipp Rietsch,Nithiya Nirmalananthan-Budau,Florian Weigert,Jan P. G?tze,Ute Resch-Genger,Siegfried Eigler,Beate PaulusPhys. Chem. Chem. Phys., 2021,23, 17521-17529 10.1039/D1CP02534A
- [9] An integrated system for field analysis of Cd(ii) and Pb(ii) via preconcentration using nano-TiO2/cellulose paper composite and subsequent detection with a portable X-ray fluorescence spectrometer? Xiaofeng LinRSC Adv., 2016,6, 9002-9006 10.1039/C5RA25693C
- [10] Aggregated-fluorescent detection of PFAS with a simple chip Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong TangAnal. Methods, 2019,11, 163-170 10.1039/C8AY02382D
Journal Name：Chemical Communications
research_products
-
CAS no.: 89640-58-4
![1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol](https://ossimg.kuujia.com/scimg/1271000/1270529-38-8x500.png)
![N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide](https://ossimg.kuujia.com/scimg/1444500/1444113-98-7x500.png)
![2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid](https://ossimg.kuujia.com/scimg/2138500/2138166-62-6x500.png)
![2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide](https://ossimg.kuujia.com/scimg/2034500/2034271-14-0x500.png)