Microwave-assisted C–N and C–S bond-forming reactions: an efficient three-component domino sequence for the synthesis of sulfoether-decorated imidazo[1,2-a]pyridines?
RSC Advances Pub Date: 2015-03-30 DOI: 10.1039/C5RA05377C
Abstract
An efficient and simple microwave-assisted three-component reaction for the formation of imidazo[1,2-a]pyridine derivatives in the presence of F3CCO2H has been described. The three-component reaction of 3-phenylpropiolaldehyde, pyridin-2-amines and thiols gives the desired products in good yields. It represents an efficient approach for the formation of C–N and C–S bonds under microwave irradiation.
![Graphical abstract: Microwave-assisted C–N and C–S bond-forming reactions: an efficient three-component domino sequence for the synthesis of sulfoether-decorated imidazo[1,2-a]pyridines](http://scimg.chem960.com/usr/1/C5RA05377C.jpg)
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Journal Name：RSC Advances
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