Micromixing enables chemoselective reactions of difunctional electrophiles with functional aryllithiums?
Reaction Chemistry & Engineering Pub Date: 2017-10-16 DOI: 10.1039/C7RE00142H
Abstract
Generation of highly unstable functional aryllithiums followed by chemoselective reactions with difunctional electrophiles were successfully achieved using flow microreactor systems equipped with micromixers to give highly functionalized compounds without protecting functional groups. Extremely fast micromixing is responsible for high chemoselectivity.
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Journal Name：Reaction Chemistry & Engineering
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CAS no.: 89640-58-4
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