Lithium triethylborohydride-promoted generation of α,α-difluoroenolates from 2-iodo-2,2-difluoroacetophenones: an unprecedented utilization of lithium triethylborohydride?
RSC Advances Pub Date: 2017-12-12 DOI: 10.1039/C7RA12130J
Abstract
Lithium triethylborohydride was found to promote the generation of α,α-difluoroenolates from 2-iodo-2,2-difluoroacetophenones, and applied to the synthesis of polyfluorinated β-hydroxy ketones via self-condensation or aldol reaction. The reaction indicates an unprecedented utilization of lithium triethylborohydride and provides novel access to the generation of α,α-difluoroenolates.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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