Iron(ii) bromide-catalyzed oxidative coupling of benzylamines with ortho-substituted anilines: synthesis of 1,3-benzazoles?
RSC Advances Pub Date: 2014-12-09 DOI: 10.1039/C4RA12490A
Abstract
An iron(II) bromide-catalyzed oxidative coupling of benzylamines with 2-amino/hydroxy/mercapto-anilines has been developed, allowing the synthesis of a diversity of substituted 1,3-benzazoles in good to excellent yields. This transformation is compatible with a wide range of functional groups. The method is practical, economical and employs molecular oxygen as an oxidant.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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