First total synthesis of Papilistatin?

Organic & Biomolecular Chemistry Pub Date: 2011-01-26 DOI: 10.1039/C0OB01214A

Abstract

Papilistatin has been isolated recently and found to have good anticancer and antibacterial activity. Papilistatin is a unique phenanthrene-1,10-dicarboxylic acid. The first total synthesis of papilistatin is described here with radical cyclisation as the key step.

Graphical abstract: First total synthesis of Papilistatin
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