First total synthesis of (?)- and (+)-6-O-desmethylantofine?
Organic & Biomolecular Chemistry Pub Date: 2010-11-04 DOI: 10.1039/C0OB00287A
Abstract
The first total synthesis of (?)-6-O-desmethylantofine (A) and its unnatural enantiomer (+)-6-O-desmethylantofine (B) is described. The synthetic route is efficient and practical with easily available glutamic acid dimethyl ester hydrochloride as the chiral material under mild conditions.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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