Facile syntheses of (+)-gabosines A, D, and E??

Organic & Biomolecular Chemistry Pub Date: 2009-10-16 DOI: 10.1039/B911810A

Abstract

(+)-Gabosines A (12), D (4), and E (5), which share the same trihydroxycyclohexenone skeleton, were synthesized from enone 11 as the common intermediate. The key building block 11 was accessed by an intramolecular aldol cyclization of a diketone derived from D-glucose (8).

Graphical abstract: Facile syntheses of (+)-gabosines A, D, and E
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