Electrohalogenation of organic compounds
Organic & Biomolecular Chemistry Pub Date: 2021-02-26 DOI: 10.1039/D0OB02459G
Abstract
Herein, we present an overview of recent advances in the electrochemical halogenation of organic compounds. Halogen-containing compounds are essential building blocks for post-functionalization in academic research and in different industrial sectors, notably pharmaceutical companies. One of the main advantages of using electrosynthesis is its environmentally-friendly characteristics. Electrosynthesis is recognized as a methodology that can fulfill different criteria of the green chemistry concept and constitutes a promising tool in the development of new procedures in organic synthesis. In this review we target sp, sp2 and sp3 carbon fluorination, chlorination, bromination and iodination reactions using electrolysis as a redox medium. Mechanistic insights and substrate reactivity are also discussed.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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