Development of and recent advances in asymmetric A3 coupling
Chemical Society Reviews Pub Date: 2019-08-29 DOI: 10.1039/C9CS00253G
Abstract
Asymmetric A3 coupling has emerged as an important class of reactions to synthesise chiral propargylamines. In this tutorial review, an up to date progress of this reaction, with significant recent advancements in terms of ligand development, is presented. Applications of asymmetric A3 coupling in natural product synthesis and in tandem processes are also discussed.
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Journal Name:Chemical Society Reviews
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CAS no.: 89640-58-4