An activity-based fluorescent sensor for the detection of the phenol sulfotransferase SULT1A1 in living cells?
RSC Chemical Biology Pub Date: 2021-03-15 DOI: 10.1039/D0CB00231C
Abstract
Human phenol sulfotransferases mediate the transfer of a sulfuryl moiety from the activated sulfate donor PAPS to hydroxy-containing substrates, altering substrate solubility and charge to affect phase II metabolism and cell signaling. Here, we present the development, computational modeling, in vitro enzymology, and biological application of STS-3, an activity-based fluorescent sensor for the SULT1A1 isoform.
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Journal Name：RSC Chemical Biology
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CAS no.: 89640-58-4
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