Tunable coordination of a troposphosphite for fine-tuning of the Rh catalyzed asymmetric addition of phenylboronic acid to cyclohexenone?

Chemical Communications Pub Date: 2008-11-19 DOI: 10.1039/B814568G

Abstract

Using the deoxycholic acid derived tropos biphenylphosphite 1 as a Rh(I) chiralligand different complexes are obtained, depending on the Rh : L molar ratio, that give rise to the formation of different chiral products in the asymmetric addition of phenylboronic acid to cyclohexenone.

Graphical abstract: Tunable coordination of a troposphosphite for fine-tuning of the Rh catalyzed asymmetric addition of phenylboronic acid to cyclohexenone
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