An efficient three-component synthesis of coumarin-3-carbamides by use of Ni–NiO nanoparticles as magnetically separable catalyst?
RSC Advances Pub Date: 2015-08-12 DOI: 10.1039/C5RA13932E
Abstract
An efficient and ecofriendly synthesis of coumarin-3-carbamides, a class of compounds known for their remarkable biological activities and fluorescent properties, has been developed by a three-component reaction of 2-hydroxybenzaldehydes, aliphatic primary/secondary amines and diethyl malonate using Ni–NiO nanoparticles as catalyst in the green solvent ethanol. The method is compatible with various functional groups and moieties.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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