Triple helix conformation-specific blinking of Cy3 in DNA?

Chemical Communications Pub Date: 2015-02-11 DOI: 10.1039/C5CC00607D

Abstract

We report that Cy3 undergoes triple helix conformation-specific blinking in DNA. Blinking patterns were affected by the stabilization of the Hoogsteen base-pair, suggesting that not only the presence but also the fluctuating behaviour of the triple helix can be monitored by the changes in the Cy3 blinking patterns.

Graphical abstract: Triple helix conformation-specific blinking of Cy3 in DNA
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