An efficient and new protocol for phosphine-free Suzuki coupling reaction using palladium-encapsulated and air-stable MIDA boronates in an aqueous medium

RSC Advances Pub Date: 2014-06-16 DOI: 10.1039/C4RA03586K

Abstract

A simple methodology that uses a system based on polyurea microencapsulated palladium (PdEnCat 30?) and aryl or (2-pyridyl) MIDA boronates for Suzuki–Miyaura cross-coupling reactions of (hetero)aryl halides in water–alcohol under phosphine-free conditions was developed.

Graphical abstract: An efficient and new protocol for phosphine-free Suzuki coupling reaction using palladium-encapsulated and air-stable MIDA boronates in an aqueous medium
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