Towards aryl C–N bond formation in dynamic thin films?

Organic & Biomolecular Chemistry Pub Date: 2014-05-23 DOI: 10.1039/C4OB00926F

Abstract

C–N bond forming reactions are important in organic chemistry. A thin film microfluidic vortex fluidic device (VFD) operating under confined mode affords N-aryl compounds from 2-chloropyrazine and the corresponding amine, without the need for a transition metal catalyst.

Graphical abstract: Towards aryl C–N bond formation in dynamic thin films
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