Total synthesis of haliclamide?
Organic & Biomolecular Chemistry Pub Date: 2016-09-02 DOI: 10.1039/C6OB01775D
Abstract
A stereoselective approach for the synthesis of haliclamide 1, a marine natural product, has been developed. The notable features of our synthesis include MacMillan cross aldol, Mitsunobu inversion, Yamaguchi–Hirao alkylation, Steglich esterification and macrolactamization reactions and the Corey–Fuchs protocol as the key steps.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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