The stability and reactivity of tri-, di-, and monofluoromethyl/methoxy/methylthio groups on arenes under acidic and basic conditions?

Organic Chemistry Frontiers Pub Date: 2016-11-16 DOI: 10.1039/C6QO00674D

Abstract

Little attention has been paid to the stability and reactivity of the C–F bond under different conditions. In this study, the stability and reactivity of tri-, di-, and monofluoromethyl/methoxy/methylthio moiety groups on arenes under acidic or basic conditions are carefully investigated.

Graphical abstract: The stability and reactivity of tri-, di-, and monofluoromethyl/methoxy/methylthio groups on arenes under acidic and basic conditions
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