An antimicrobial bicyclic peptide from chemical space against multidrug resistant Gram-negative bacteria?
Chemical Communications Pub Date: 2018-04-23 DOI: 10.1039/C8CC02412J
Abstract
We used the concept of chemical space to explore a virtual library of bicyclic peptides formed by double thioether cyclization of a precursor linear peptide, and identified an antimicrobial bicyclic peptide (AMBP) with remarkable activity against several MDR strains of Acinetobacter baumannii and Pseudomonas aeruginosa.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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