Synthesis of substituted naphthalenes from α-tetralones generated by a xanthate radical addition–cyclisation sequence

Organic & Biomolecular Chemistry Pub Date: 2004-09-27 DOI: 10.1039/B411158C

Abstract

A simple, highly efficient and cheap synthesis of substituted naphthalenes is reported. These aromatic compounds can be easily prepared in acidic or basic conditions from α-tetralones, obtained by a xanthate-mediated addition–cyclisation sequence.

Graphical abstract: Synthesis of substituted naphthalenes from α-tetralones generated by a xanthate radical addition–cyclisation sequence
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