Synthesis, photophysical and anticancer study of D-ring extended estrone analogues?

RSC Advances Pub Date: 2015-08-04 DOI: 10.1039/C5RA11112A

Abstract

A concise route for the highly substituted ring extended estrone derivatives has been established. This protocol involves very simple, facile and one step ring transformation and cyclization process. The preliminary absorption, emission spectroscopic and biological studies of these compounds revealed the possible use of such prototypes in cancer chemotherapy as fluorescence probes.

Graphical abstract: Synthesis, photophysical and anticancer study of D-ring extended estrone analogues
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