Synthesis of 2-trifluoromethylquinolines via copper-mediated intramolecular oxidative cyclization of N-(2-alkenylaryl) enamines?
RSC Advances Pub Date: 2016-05-12 DOI: 10.1039/C6RA09741C
Abstract
A general and efficient copper-mediated intramolecular oxidative cyclization of N-(2-alkenylaryl) enamines for the synthesis of 2-trifluoromethylquinolines has been developed. The targeted heterocycle is a privileged structure in many natural compounds and drugs with a broad range of biological activities.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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