Synthesis of ureas in the bio-alternative solvent Cyrene?
Green Chemistry Pub Date: 2017-04-24 DOI: 10.1039/C7GC00908A
Abstract
Cyrene as a bio-alternative solvent: a highly efficient, waste minimizing protocol for the synthesis of ureas from isocyanates and secondary amines in the bio-available solvent Cyrene is reported. This method eliminated the use of toxic solvents, such as DMF, and established a simple work-up procedure for removal of the Cyrene, which led to a 28-fold increase in molar efficiency versus industrial standard protocols.
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Journal Name：Green Chemistry
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CAS no.: 89640-58-4
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