Concise synthesis of cyclic carbonyl compounds from haloarenes using phenyl formate as the carbonyl source?

Chemical Communications Pub Date: 2014-12-08 DOI: 10.1039/C4CC09413A

Abstract

Various cyclic carbonyl compounds were concisely synthesized by carbonylative cyclization of haloarenes bearing nucleophilic moieties under Pd catalysis. A broad substrate scope and a feasible large-scale synthesis clearly demonstrate the high applicability of the reaction as a general, user-friendly method for access to cyclic carbonyl compounds.

Graphical abstract: Concise synthesis of cyclic carbonyl compounds from haloarenes using phenyl formate as the carbonyl source
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