Synthesis and chemistry of enantiomerically pure 10,11-dihydrodibenzo[b,f]thiepines

Organic & Biomolecular Chemistry Pub Date: 2006-05-03 DOI: 10.1039/B516606C

Abstract

Several chiral thiepines were efficiently constructed using sulfur diimidazole in combination with a variety of bislithiated carbon fragments. The sulfur atom in these thiepines is found to be unusually unreactive compared to diphenylsulfide.

Graphical abstract: Synthesis and chemistry of enantiomerically pure 10,11-dihydrodibenzo[b,f]thiepines
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