Synthesis of characteristic lipopeptides of lipid modified proteins employing the allyl ester as protecting group

Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A708749G

Abstract

Lipidated peptides which represent characteristic lipid modified substructures of lipidated human GαO protein and the human N- and R-Ras proteins were built up efficiently by employing the selective Pd0-mediated removal of allyl esters under very mild conditions as the key step.

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