α-Functionalization of ketones promoted by sunlight and heterogeneous catalysis in the aqueous phase?
Organic & Biomolecular Chemistry Pub Date: 2021-12-23 DOI: 10.1039/D1OB02249K
Abstract
Herein, a protocol that combines heterogeneous catalysis and solar photocatalysis for the regioselective α-substitution of asymmetric ketones with quinoxalinones has been reported. The result indicates that the reaction is more likely to occur on the α-carbon. This strategy provides a green and efficient way for the α-functionalization of ketones. A singlet oxygen involved mechanism is suggested for the transformation.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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