Synthesis of novel polymerizable molecules bearing bisphosphonate?

Organic & Biomolecular Chemistry Pub Date: 2015-09-29 DOI: 10.1039/C5OB01967B

Abstract

In recent years, bisphosphonate chemistry has undergone an exponential growth due to the potential applications of these compounds in medicine and nanobiomaterial research. In this paper we describe the synthesis methods of different families of methacrylic monomers bearing a bisphosphonate with varying lengths of the chain, PEG linkers and more or less hydrolysable functions such as ester, carbamate or amide.

Graphical abstract: Synthesis of novel polymerizable molecules bearing bisphosphonate
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