Synthesis of indoles via dehydrogenative N-heterocyclization by supported platinum catalysts?

RSC Advances Pub Date: 2014-11-25 DOI: 10.1039/C4RA11893F

Abstract

We found the first heterogeneous Pt catalysts (Pt/Nb2O5 and Pt/HBEA) for the synthesis of indoles via acceptorless dehydrogenative cyclization of 2-(2-aminophenyl)ethanol, showing higher turnover number (TON) than previously reported catalysts.

Graphical abstract: Synthesis of indoles via dehydrogenative N-heterocyclization by supported platinum catalysts
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