Synthesis of glycosylphosphatidylinositol (GPI)-anchor glycolipids bearing unsaturated lipids?
Chemical Communications Pub Date: 2015-11-30 DOI: 10.1039/C5CC07694C
Abstract
2-Naphthyl-methyl ethers as permanent protecting groups are readily removed under acidic conditions and are key to the synthesis of complex glycosylphosphatidylinositol anchors containing unsaturated lipids. The total synthesis of the GPI pseudo-disaccharide core found on the surface of the Trypanosoma cruzi parasite serves to illustrate the power of the strategy.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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