Synthesis and anticancer activity of prodigiosenes bearing C-ring esters and amides?
RSC Advances Pub Date: 2017-03-27 DOI: 10.1039/C7RA01628J
Abstract
Prodigiosenes, a class of compounds characterised by their 4-methoxypyrrolyldipyrrin framework, are known to possess anti-cancer activity. Structural modification of the C-ring of prodigiosenes presented ten new prodigiosenes bearing pendant alkyl esters and amides. These prodigiosenes were evaluated biologically and displayed notable anticancer in vitro activity, particularly when featuring a hexyl chain.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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