Taxol, a molecule for all seasons
Chemical Communications Pub Date: 2001-03-26 DOI: 10.1039/B100070P
Abstract
The diterpenoid natural product taxol, first discovered in the 1960’s has proved to be the most important new anticancer drug introduced in the last ten years. A brief history of taxol’s development from laboratory curiosity to blockbuster drug is followed by a summary of its chemistry, including an overview of the six completed syntheses of taxol. The review concludes with a discussion of its bioactivity as a promoter of tubulin polymerization and as a drug.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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