Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

Natural Product Reports Pub Date: 2012-10-09 DOI: 10.1039/C2NP20060K

Abstract

Covering: up to December 2011

This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.

Graphical abstract: Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs
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