Aerobic oxidative decyanation–amidation of arylacetonitriles with urea as a nitrogen source?
Organic Chemistry Frontiers Pub Date: 2016-12-13 DOI: 10.1039/C6QO00635C
Abstract
An iron-catalyzed aerobic oxidative amidation reaction of the inert C–CN bond of aryl acetonitriles to afford aryl amides has been developed. Urea is used as an efficient and convenient nitrogen source. This reaction provides practical access toward amide synthesis.
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Journal Name:Organic Chemistry Frontiers
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CAS no.: 89640-58-4