Stereochemical effects of chiral monolayers on enhancing the resistance to mammalian cell adhesion?

Chemical Communications Pub Date: 2011-04-26 DOI: 10.1039/C1CC10855G

Abstract

This work describes the different durations of surface confinement of adhered mammalian cells by monolayers comprised of enantiomers of bio-inert polyol-terminated alkanethiols. Enhanced resistance to protein adsorption and cell adhesion is obtained on monolayers formed by a racemic mixture of the enantiomeric alkanethiols.

Graphical abstract: Stereochemical effects of chiral monolayers on enhancing the resistance to mammalian cell adhesion
Recommended Literature