Ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions?

Green Chemistry Pub Date: 2012-09-04 DOI: 10.1039/C2GC36095K

Abstract

A facile, efficient and environmentally-friendly protocol for the synthesis of α-acyloxy amides has been developed by ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions. This method provides several advantages over current reaction methodologies including a simpler work-up procedure, shorter reaction times and higher yields.

Graphical abstract: Ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions
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