Small molecule detection by lateral flow strips via aptamer-gated silica nanoprobes
Analyst Pub Date: 2016-03-18 DOI: 10.1039/C6AN00273K
Abstract
A fast, sensitive and ratiometric biosensor strategy for small molecule detection was developed through nanopore actuation. The new platform engineers together, a highly selective molecular recognition element, aptamers, and a novel signal amplification mechanism, gated nanopores. As a proof of concept, aptamer gated silica nanoparticles have been successfully used as a sensing platform for the detection of ATP concentrations at a wide linear range from 100 μM up to 2 mM.
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Journal Name：Analyst
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CAS no.: 89640-58-4
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