Well-defined palladium(ii) complexes for ligand-enabled C(sp3)-alkynylation?

Dalton Transactions Pub Date: 2015-07-22 DOI: 10.1039/C5DT02772A

Abstract

The first example of ligand-enabled C(sp3)-alkynylation of 8-methylquinoline is reported. The reaction is catalysed by well-defined Pd(II) complexes. The present C(sp3)-alkynylation has a broad substrate scope as well as functional group tolerance and proceeds efficiently under mild conditions.

Graphical abstract: Well-defined palladium(ii) complexes for ligand-enabled C(sp3)-alkynylation
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