Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold?
RSC Advances Pub Date: 2020-08-06 DOI: 10.1039/D0RA05105E
Abstract
An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4H-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four new heterocycles via ten covalent bonds in a single step.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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