Acridinone-based anion transporters??
Organic & Biomolecular Chemistry Pub Date: 2021-09-13 DOI: 10.1039/D1OB01545A
Abstract
The arrangement of hydrogen bond donors around a central lipophilic scaffold has proven to be a successful strategy in the development of potent chloride transporters. In this work, we revisit an acridinone 1,9-bis(thio)urea motif which had previously shown promise as an anion sensor and expand the series of compounds by appending a variety of electron-withdrawing groups to the peripheral phenyl moieties. High levels of activity were achieved by the most effective compounds in the series, which facilitated strictly electroneutral transport.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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